Sustainable production of camptothecin from an Alternaria sp. isolated from Nothapodytes nimmoniana

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Direct analysis of camptothecin from Nothapodytes nimmoniana by desorption electrospray ionization mass spectrometry (DESI-MS).

Desorption electrospray ionization was employed for fast and direct ambient detection of the anti-tumor drug, camptothecin, and its derivative, 9-methoxycamptothecin in Nothapodytes nimmoniana. Different parts of the plant such as leaves, stems and bark were examined. The ion intensities suggest that the concentration in bark is higher than that in the leaves and stems. The method does not requ...

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Compound Specific Extraction of Camptothecin from Nothapodytes nimmoniana and Piperine from Piper nigrum Using Accelerated Solvent Extractor

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Influence of Geographical and Climatic Conditions on Camptothecin Content of Nothapodytes nimmoniana

Camptothecin, topoisomerase I-DNA inhibitor, has been evaluated in methanolic extract of various parts of Nothapodytes nimmoniana (J. Graham) Mabberly (Family Icacinaceae) collected in the month of February from different regions (Mahabaleshwar and Patan regions of Maharashtra state and Sirsi region of Karnataka state) of Western Ghats, India, using high performance liquid chromatography. Quant...

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Production and purification of a protease from an alkalophilic Bacillus sp. 2-5 strain isolated from soil

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Seasonal Discrepancy in Phenolic Content and Antioxidant Properties from Bark of Nothapodytes Nimmoniana (grah.) Mabb

Seasonal discrepancy in the antioxidant potential from bark of Nothapodytes nimmoniana was evaluated using two different methods (DPPH and FRAP) and were related to total phenolic content as well as flavonoid content. Higher yield of phenolic and flavonoid were observed during summer (May) similarly, the antioxidant activities (DPPH & FRAP) also were high. The antioxidant activities were strong...

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ژورنال

عنوان ژورنال: Scientific Reports

سال: 2021

ISSN: 2045-2322

DOI: 10.1038/s41598-020-79239-5